مقاله Hypertonic 3% Saline in Comparison with 0.9% (Normal) Saline in Treatment of Acute Bronchiolitis

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توجه : در صورت  مشاهده  بهم ریختگی احتمالی در متون زیر ،دلیل ان کپی کردن این مطالب از داخل فایل ورد می باشد و در فایل اصلی مقاله Hypertonic 3% Saline in Comparison with 0.9% (Normal) Saline in Treatment of Acute Bronchiolitis،به هیچ وجه بهم ریختگی وجود ندارد

بخشی از متن مقاله Hypertonic 3% Saline in Comparison with 0.9% (Normal) Saline in Treatment of Acute Bronchiolitis :

سال انتشار : ۲۰۱۷

تعداد صفحات :۱۳

BackgroundBronchiolitis is the commonest cause of lower respiratory tract infection in infant. Respiratory syncytial virus is the commonest cause of bronchiolitis. This study aimed to assess the efficacy of nebulized 3% hypertonic saline and salbutamol in the treatment of acute bronchiolitis in comparison with nebulized 0.9% saline and salbutamol.Materials and MethodsA prospective case second multicenter study was done at two pediatric tertiary centers at the period from 1st of December 2014 to 31 of March 2015. A total of 100 previously well infant and children of age 1-24 months with clinical diagnoses of bronchiolitis who were admitted to the hospital were included. They were divided into two groups, the study group received 4 ml of nebulized hypertonic 3% saline (for 14 days), and second group received 4 ml of nebulized normal 0.9% saline (for 14 days), each co-administer with 0.5 ml salbutamol.ResultsAll patients with acute bronchiolitis having similar baseline characteristic, mean age 4.9 + Standard deviation (SD) months, male gender constitutes 68% of the patients and the majority (67%) of the cases were below 6 months. The mean of clinical severity score at admission was 6.4 for normal saline (NS) group and 6.6 for hypertonic 3% saline (HS) group. The mean length of hospital stay of normal saline group = 4.3 + Standard deviation (SD) day and for hypertonic saline group was = 4.7 + Standard deviation (SD) day.ConclusionWe didn’t find any advantage of hypertonic 3% saline over 0.9% normal saline in terms of length of hospital stay and clinical severity score.