مقاله Glutathione S-transferase Polymorphisms and Bone Tumor Risk in China

مقاله Glutathione S-transferase Polymorphisms and Bone Tumor Risk in China

… دانلود …

 مقاله Glutathione S-transferase Polymorphisms and Bone Tumor Risk in China دارای 6 صفحه می باشد و دارای تنظیمات در microsoft word می باشد و آماده پرینت یا چاپ است

فایل ورد مقاله Glutathione S-transferase Polymorphisms and Bone Tumor Risk in China  کاملا فرمت بندی و تنظیم شده در استاندارد دانشگاه  و مراکز دولتی می باشد.

توجه : در صورت  مشاهده  بهم ريختگي احتمالي در متون زير ،دليل ان کپي کردن اين مطالب از داخل فایل ورد مي باشد و در فايل اصلي مقاله Glutathione S-transferase Polymorphisms and Bone Tumor Risk in China،به هيچ وجه بهم ريختگي وجود ندارد


بخشی از متن مقاله Glutathione S-transferase Polymorphisms and Bone Tumor Risk in China :

سال انتشار : 2011

تعداد صفحات :6

Aim: We aimed to study the potential role of GSTM1 and GSTT1 in the risk of osteosarcoma in Chinese population. Methods: We collected 110 osteosarcomas by pathologic examination and 226 controls from the First Affiliated Hospital of Harbin Medical University during December 2008 to December 2010. Genotyping was based upon duplex polymerase-chain-reaction with the PCR-CTPP method. Results: Individuals carrying null GSTM1 and GSTT1 had 1.50 and 2.07 fold risks of osteosarcoma when compared with non-null genotypes, respectively. The increased risk associated with the GSTT1 polymorphism seemed more evident among males (Null GSTT1 genotype vs. non-null genotype, adjusted OR= 2.43, 95% CI: 1.29-3.30) than females (adjusted OR =1.66, 95% CI: 1.02-2.78). The increased risk was also more evident among individuals aged 15 years or less (adjusted OR for null GSTT1 genotype vs. non-null genotype = 2.24, 95% CI: 1.20-3.24) than those aged more than 15 years (adjusted OR = 1.82, 95% CI: 1.07-2.95). Conclusion: Our study of the association between polymorphisms in GSTM1 and GSTTI and the risk of osteosarcoma in a Chinese population provided evidence that null GSTTI might be a useful marker of susceptibility to osteosarcoma development, especially for male sand young age individuals.

با سلام،محصول دانلودی nx آماده ارائه به شما پژوهنده عزیز میباشد.با کلیک روی دکمه ادامه مطلب به صفحه توضیحات کامل nx هدایت میشوید
nx